ABSTRACT
The major challenge in combining multiple chemical transformations is the compatibility of different reagents and catalysts. One approach for a successful reaction sequence is to search for two or more compatible reactions. Thus, none of the chemicals present in the mixture inhibit another reaction in the sequence. Many combinations of compatible reactions have been reported in the literature [11-14]. In a remarkable example described by Orru, an eight-component one-pot reaction was carried out with a total reaction yield of 24% (Fig. 4.2) [17].
