ABSTRACT

However, most antibiotics kill the microorganisms by cell wall damage as well as inhibition of cellular processes essential for survival, which leads to a strong selective pressure to develop resistance against antibiotics. In other words, the long-term use of large quantities of different antibiotics has contributed to antibiotic resistance in both agriculturally and medically important bacteria, including in Pseudomonas aeruginosa and Staphylococcus aureus. Therefore, society urgently needs an alternative approach to develop effective therapies against microbial pathogens without affecting their growth in order to avoid creating antibiotic-resistant bacteria in any species that belongs to animals or plants (Keyser et al., 2008).