ABSTRACT

Some of the microorganisms are known to produce several metabolites with different structures and biological activities, and a single microbial strain may produce more than one secondary metabolite. The compounds produced by one particular strain may have similar chemical structures or completely different structures. Microorganisms contain cluster of genes for the formation of each secondary metabolite. Each cluster has genes encoding structural biosynthetic enzymes and regulatory proteins for the control of

3.8 Secondary screening for antimicrobial compounds ......................................................43 3.9 Identication and characterization of antimicrobial metabolites .................................43