ABSTRACT

D. DZIDZIGIRI, M. RUKHADZE, I. MODEBADZE, N. GIORGOBIANI, L. RUSISHVILI, G. MOSIDZE, E. TAVDISHVILI, and E. BAKURADZE

Department of Biology Faculty of Exact and Natural Sciences, Iv. Javakhishvili Tbilisi State University, Tbilisi, Georgia, E-mail: d_dzidziguri@yahoo.com

30.1 Introduction ................................................................................ 395 30.2 Experimental Part ....................................................................... 396 30.3 Results and Discussion .............................................................. 397 30.4 Conclusions ................................................................................ 400 Keywords .............................................................................................. 400 References ............................................................................................. 400

30.1 INTRODUCTION

Identification of the functions of proteins and other polymeric complexes or cell proteomes, in which the achievements of proteomics contributes

greatly, is the subject of intensive research. [13]. Modern technology now allows us to investigate not only individual protein molecules in living cell, but also to understand their interaction with other macromolecules and reveal their previously unknown functions. Several facts are determined: participation of polyfunctional macromolecular protein complexes in the biosynthesis of fatty acids, involvement of erythrocyte membrane proteins macromolecular complexes in exchange of CO2/O2, biological effects of some growth factors (polyfunctional proteins), which sometimes is achieved by interactions of other protein complexes, etc. ([4, 5]; https:// belki.com.ua/belki-struktura.html).