ABSTRACT
Introduction ................................................................................................................................. 290 Genetic variation in human population .................................................................................. 290
Genome variation and susceptibility to disease ................................................................ 291 Genome variation and response to drugs: The era of personalized medicine .............. 292 Genome-wide association studies ....................................................................................... 293 Transcriptional proling ........................................................................................................ 293 Regulating RNAs and enhancers ......................................................................................... 294 Data storage and analysis challenges .................................................................................. 294 Omics data sharing ................................................................................................................ 294 Challenges of personalized medicine in developed and developing countries ........... 295 Patient cohorts and biobanking ........................................................................................... 296
Conclusion ................................................................................................................................... 297 References .................................................................................................................................... 298
for an individual in the future. Currently, scientists are also facing huge challenges-generating faster data, storing and analyzing huge data sets, creating meaningful inferences from the data-all in time for a patient to receive treatment tailored for him or her.
