ABSTRACT

Diabetes mellitus ......................................................................................................................... 378 Prevalence of diabetes ........................................................................................................... 378 Etiology and diagnosis of T2D ............................................................................................. 378 Pathophysiology of T2D ........................................................................................................ 379 An overview of pancreas functional biology ..................................................................... 379

Insulin and glucagon ........................................................................................................ 379 Insulin secretion in response to glucose .........................................................................380 Insulin mechanism of action ............................................................................................380 Insulin resistance ...............................................................................................................380