ABSTRACT

The human placenta is a unique organ that bears limited anatomical resemblance to the placentae of common laboratory animals. The correct function of the human placenta is key for adequate nutrient and gas exchange between mother and baby, and thus for the overall success of pregnancy. The human placenta has a villous or branching structure and is hemochorial, meaning that the fetal trophoblast of the placenta is in direct contact with the maternal blood during most of pregnancy. The ability of the placenta to achieve appropriate transfer at the end of pregnancy depends on adequate placental development in early pregnancy. The umbilical cord connecting the fetus and placenta is formed in the first 8 weeks of gestation. The human placenta is a fascinating organ, the correct function of which is crucial to the success of all pregnancies and to the future health of the offspring.