ABSTRACT

Biological sensing elements, or biosensors, have been used to

monitor gene expression in many applications and scenarios [1, 2].

Their areas of application seem only constrained by scientific cre-

ativity. Yet, in terms of practicality, many sensors require additional

information, such as determination of enzyme activity, continuous

sampling for activity evaluation, or even the addition of exogenous

reagents. In this regard, the use of certain biosensors can be time

consuming, intricate, and cumbersome. A truly viable biosensor

would include elements that are rapid, noninvasive, and sensitive

and can be conducted as real-time reporters of probed activity.