ABSTRACT
Cell membrane lipids are involved in a variety of cellular activities.
However, the role of membrane lipids in drug discovery and
drug delivery has not been fully explored. In this chapter, we
review biophysical interactions of drugs and nanoparticles with
membrane lipids and discuss how these interactions influence
drug delivery. Biophysical interaction studies can improve our
understanding of the role of membrane lipids in the transport of
drugs/nanocarriers across biological barriers and can provide a
simple yet effective mechanistic and rational approach for designing
efficient drugs/nanocarrier systems for targeting.
