ABSTRACT
Membrane fusion is a crucial event occurring between lipid
membranes in living organisms. However, so far very few drug
delivery systems have been identified to spontaneously fusewith the
plasmalemma of cells. The fusion process is often associated with
endocytic mechanisms. After a physical description of membrane
fusion, this chapter reviews all the natural or synthetic vectors that
fuse with membranes, spontaneously or with physical assistance.