ABSTRACT
Therapeutic molecules can refer to just about any molecular agent
that produces a therapeutic effect, including small-molecule drugs
currently used in the clinic, as well as antibodies, peptides, proteins,
toxins, and nucleic acids. Studies related to the delivery of any of
these agents in recent years have reflected a better appreciation of
endocytic processes facilitating drug efficacy, in particular, because
of their ability to avoid drug efflux and degradative pathways.
Invasive bacteria and viruses have evolved means to evade such
cell defense pathways; hence it helps to examine the intracellular
transport mechanisms used by these pathogens that may contribute
to enhanced drug delivery.
