ABSTRACT
M.E. Navakouski,2,j M.A. Nikolaeva,1,b N.E. Kan,1,c O.V. Vavina,1,d A.V. Nikolaeva,1,e V.L. Tyutyunnik,1 N.V. Tyutyunnik,1,f I. Bot,3
G.T. Sukhikh1,g and N.V. Bovin2,k
Pre-eclampsia (PE) is a multisystem pathological state with clinical signs being displayed after week 20 of pregnancy. The symptoms are characterized with arterial hypertension in combination with proteinuria (≥ 0.3 g/l in daily urine), often with edemas, and manifestations of multiorgan/multisystemic failures (Magee et al. 2014). PE can be complicated with eclampsia, HELLP-syndrome, acute renal failure, pulmonary edema, stroke, intrauterine growth retardation, abruption of placenta and antenatal intrauterine fetal death (Chaiworapongsa et al. 2014). PE is one of the main causes of maternal and perinatal morbidity and mortality
1 Federal State Budget Institution «Research Center for Obstetrics, Gynecology and Perinatology» of Ministry of Healthcare of the Russian Federation, Moscow, 117997, Oparin street, 4.
