ABSTRACT
Solvation is an elementary process in nature and is particularly
essential to biology. Physically, the solvation process can be
described by a variety of interactions, such as electrostatic, dipolar,
induced dipolar, and van der Waals, between the solvent and solute.
Due to the ubiquitous nature of electrostatics and the aqueous
environment common to most biomolecular systems, molecular
solvation and electrostatics analysis is significantly important to
research in chemistry, biophysics, and medicine. Such analyses can
be classified into two general types: (1) quantitative analysis for
thermodynamic or kinetic observables and (2) qualitative analysis
for general characteristics of biomolecular solvation.
