ABSTRACT

The liver is one of the largest internal organs and performs critical biochemical functions in the body. It is composed of complex microstructures wherein various cells and components reside in an exquisitely aligned manner. Bioprinting represents a promising approach for the fabrication of artificial liver constructs that mimic the complex structure of native liver tissue. In this chapter, we introduce liver-cell sources and biomaterials for liver bioprinting. We also discuss different techniques for liver bioprinting and their applications, which include transplantable liver constructs and in vitro drug-screening models.