ABSTRACT

Medicinal plants are the source of an enormous variety of bioactive secondary metabolites and have potential synergistic effects against a broad range of human diseases. This chapter provides a compilation of advances in both conventional and modern omics approaches for Artemisinin (AN) yield enhancement such as various structural and functional genomics approaches, proteomics approaches, metabolomics approaches for identifying the players involved in regulation of AN biosynthesis. It also include: and integrated breeding of A. annua with the help of molecular markers. Proteomics provides a powerful tool for the study of proteins on a genome-wide scale. The field of proteo-genomics is important due to its potential to support the annotation of DNA sequence data by exploiting the information obtained through proteomic studies for the identification/characterization of the actual products of gene expression. Many omics platforms target the comprehensive analysis of genes, mRNA, proteins, and metabolites. However, the interpretation of obtained data is challenging due to very complex biochemical and metabolic pathways.