ABSTRACT
Leptospirosis is zoonoses of ubiquitous distribution that affect both animals and humans and which are transmitted from reservoir hosts to accidental hosts. It has various clinical manifestations, including abortion, still birth, systemic disease with hepatic or renal dysfunction, and uveitis. Uveitis is a general term describing a group of inflammatory diseases that produces swelling and destroys eye tissues. These diseases can slightly reduce vision or lead to severe vision loss among humans. Among horses uveitis is also a severe complication and leads to moon blindness. Equine recurrent uveitis (ERU) is the most frequently encountered clinical manifestation with a reported prevalence of 2%–25% worldwide, whereas subconjunctival haemorrhage, chorioretinitis, papilledema, papillitis, optic neuritis, retinal bleed, and cotton-wool spots are other manifestations of leptospirosis in the eyes. Recurrent episodes usually result from dysregulated immune responses within the eye as a result it often causes blindness. Diagnosis of leptospira-associated ERU requires combination of tests and the early detection prevent from serious complications. The prognosis for sight may be better with medical and surgical treatment.
Keywords: haemorrhage, leptospirosis, ophthalmic, uveitis
