ABSTRACT

A sustainable and economical method for the renewable production of biofuels is desirable to sustain the increasing global population and economy with a smaller carbon footprint. Systems biology along with new engineering technologies can provide ways to generate chemicals of great significance such as advanced biofuels. Producing these important biofuels in high yields requires the correct engineering of, for example, a yeast cell’s metabolism. Removing bottlenecks in yeast metabolic pathways and relieving the stresses due to production of the advanced biofuels are fundamental in the generation of efficient industrial-scale production hosts. Systems-level research can reveal an understanding of the metabolic pathway. However, a number of challenges remain before advanced biofuels can be used commercially and economically.