ABSTRACT
Both primary and secondary tumors are known to affect the appendix. The most common primary appendiceal cancer is carcinoid, which accounts for about 65" of all appendiceal malignancies. The human appendix is a narrow pouch of tissue extending from the cecum located in the lower right-hand abdominal area. Most primary adenocarcinomas of the appendix evolve from adenomatous polyp or serrated adenoma. Appendiceal tumors often cause appendicitis or rupture of appendicitis, with acute pain and tenderness in the right lower quadrant as typical symptoms. Surgical excision offers an effective treatment for appendiceal tumors, both benign and malignant. The tumor may be referred to as low-grade appendiceal mucinous neoplasm (LAMN) in cases of well-differentiated mucinous neoplasm without evidence of frank invasion or absence of tumor cells in mucin deposits. Carcinoids arise from neuroendocrine cells located in the small intestine, rectum, appendix, colon and stomach.
