A field experiment was conducted at BCKV, Regional Research Station, New Alluvial Zone, Gayeshpur, Nadia, West Bengal during the nabi season of 2013–2014 to study “the effect of different nutrient management on productivity of potato (var. KufriJyoti) and soil nutrient status in New Alluvial 218Zone of West Bengal.” The experimental site area was sandy clay loam soil in texture having good drainage with medium soil fertility. The experiment was carried out in a randomized block design by replicating thrice of eight treatments, i.e., T 1: 50% recommended NPK (inorganic) + 50% N as FYM; T 2: 1/3rd recommended N each from farm yard manure (FYM), vermicompost (VC), neem cake (NC); T 3: T 2 + intercropping (potato + coriander–1:1); T 4: T 2 + straw mulch for weed management; T 5: 50% N as FYM + Rock phosphate + phosphorus solubilizing bacteria (PSB) (+ Azotobacter); T 6: T 2 + biofertilizers containing N and P carriers (same as T 5); T 7: 100% recommended NPK; and T 8: Control (without manures and fertilizers). Among the different treatments, T 7 (100% recommended NPK) gave the highest plant height, dry matter accumulation, CGR, number of tubers per hill, and tuber bulking rate but was found statistically at par with integrated nutrient management, i.e., T 1 (50% recommended NPK (inorganic) + 50% N as FYM). The maximum tuber yield of 22.19 t ha−1 was produced in T 7, which was statistically at par with T 1 (20.99 t ha−1). Soil chemical properties like organic carbon, N, P, and K content were found appreciably higher under organic treatments over the initial status. Among the different organic-based nutrient managements, T 6 gave the highest organic carbon (0.91%), N (0.076%), P (20.58 kg ha−1), and K (175.57 kg ha−1). Therefore, it was concluded that in order to sustain the productivity of soil and crops for long-term basis, organic nutrient management are the best options followed by integrated nutrient management.