ABSTRACT
The ILT Safe-Cross radiofrequency (RF) system is a steerable fiberoptic guidewire system that is able to ‘look forward’, recognize arterial wall, and deliver RF energy to the Chronic total occlusions (CTO) for the ultimate goal of recanalization. Optical coherence reflectometry is a one-dimensional ranging method applied to studies in fiber-based waveguide devices. The GRIP trial was a multicenter prospective randomized study of the feasibility and safety of the ILT Safe-Cross device. Percutaneous options are often preferred by patients and their physicians because of the minimally invasive approach. This approach leads to expedited recovery, quicker time to ambulation, and the ability to preserve conduits, such as saphenous veins, for later possible use. Stenting CTOs at flexion points has the inherent risk of stent fracture and possible increase of in-stent restenosis. For this reason, at flexion points, in particular, the ILT Safe-Cross ensures advancement of the system within the lumen, eliminating stent-requiring dissections.
