ABSTRACT

Testosterone has traditionally been regarded as a hormone that is harmful to the heart, in the same way that estrogen is perceived as a hormone that is good for the heart.1 The development of androgen therapies for men has often struggled against the perception that any benefit in terms of improved sexual function or protection from osteoporosis, for example, will be at a cost of myocardial infarction and strokes, in addition to concern over prostatic disease. In fact this has never been a unanimous concern: a vocal minority, increasingly evident on the internet,2 extols the virtue of androgens as treatments for these very same diseases.