ABSTRACT
Definition of chronic renal insufficiency • Impact of chronic renal insufficiency on outcomes after percutaneous coronary intervention • Hemorrhagic complications in relation to chronic renal insufficiency • Adjunctive pharmacotherapy during percutaneous coronary intervention in patients with chronic renal insufficiency • Long-term outcomes post-percutaneous coronary intervention in relation to chronic renal insufficiency • Frequency of angiographic and clinical restenosis in patients with chronic renal insufficiency • Drug-eluting stents in patients with chronic renal insufficiency • Renal function deterioration post-percutaneous coronary intervention in patients with chronic renal insufficiency: contrast-induced nephropathy • Prevention of contrast-induced nephropathy • Targeted renal therapy • Conclusion
Chronic renal insufficiency (CRI) is a prevalent condition in patients undergoing percutaneous coronary revascularization. In a pooled analysis of contemporary trials on percutaneous coronary intervention (PCI), CRI at baseline was present in approximately 25% of the patients,1 and among patients undergoing primary PCI for acute myocardial infarction (MI), about 20% of the study population had baseline CRI.2 Despite the high prevalence of CRI in the PCI series, no study assessed prospectively the outcomes of these patients, while the current data are available from the post hoc analyses from controlled randomized trials, registries, and observational studies.
