ABSTRACT

The transcriptome is composed of all mRNA molecules that are transcribed from genes in a given tissue, cell, or organism, under a specified set of conditions.1

The study of transcriptomics examines mRNA levels, usually using high-throughput techniques based on DNA microarray technology.2 With sequencing of the human genome and major technological advances in simultaneously analyzing large data sets and large numbers of genes and their products, the post-genomic era has heralded a revolution in global gene expression analysis and sophisticated bioinformatic approaches to mine data and enable understanding of biological processes, key regulators, biochemical pathways, and subcellular constituents involved in the expression of specific genes and gene families.3 Several reviews on the application of these technologies to reproductive medicine have recently been published.4-9 Application to the endometrium is presented herein.