ABSTRACT

Case 2: RCM mosaic (2 mm × 2 mm) at the level of the DEJ reveals perifollicular, irregular aggregates of bright cells (yellow arrows), junctional cell clusters (white arrows), junctional thickening (red arrow), and areas with effacement of the normal architecture (circled). Corresponding conventional (10×) and Melan-A immunohistochemically stained histology (10×) show a high density of melanocytes as single units and nests along the DEJ and extending down follicular epithelium (yellow arrows). Rare melanocytes can be seen scattered at all levels of the epidermis (black arrows).