ABSTRACT

Neuropsychological examinations have long been an integral part of pre-surgical epilepsy evaluations. The assessment of pre-surgical cognitive functioning can provide supplemental information about seizure lateralization and localization and help to identify patients who are at risk of cognitive decline following surgical treatment for intractable focal epilepsy. The purpose of this chapter is to discuss the factors that are related to cognitive outcome in adults following epilepsy surgery and to summarize existing literature on multivariate prediction of post-operative cognitive risk.