ABSTRACT
Diagnosis Fibrosarcoma represents a wide spectrum of soft tissue sarcomas. Diagnosis is essentially made as with any other soft tissue sarcoma. The site distribution is as in Figure 3.1, and the age distribution as previously described in Figure 3.2. Often there are a number of other associated pathologic subtypes, such as inflammatory fibrosarcoma, inflammatory pseudo-tumor, or inflammatory myofibroblastic tumor. It is important to make the diagnosis, because, despite their appearance, inflammatory tumors often have an excellent prognosis following complete resection. Increasingly, the myxofibrosarcoma variant has been diagnosed, to include many lesions previously classified as MFH (Figure 7.24). This differential diagnosis is consistent with the concept of an exuberant repair process and clinically often blends into some aspects of the fibromatoses, although the primary cell type involved is the myofibroblast.
