ABSTRACT

Introduction Despite dramatic improvements in survival rates neoplasia continues to be a major cause of childhood mortality.1 Nephroblastoma (Wilms’ tumour), a common solid tumour of childhood, has an incidence of approximately 7 in one million. Treatment regimens with combinations of surgery and chemotherapy with or without radiotherapy have been developed within international protocols,2-5 leading to a remarkable improvement in overall survival from < 10% in 1935 to > 85% in 1996.6,7 These children undergo numerous procedures during their treatment, many requiring anaesthesia. The following case depicts the clinical course of a child from presentation.