ABSTRACT

The European Diabetes Policy Group 1998-1999 have produced

straightforward guidelines1 and a diagnostic algorithm for diabetes

mellitus (Fig 13).

Cautions Diagnosis must be confirmed by laboratory plasma glucose

readings;

The diagnosis must be based on two abnormal glucose

concentrations in the absence of symptoms;

Diagnostic procedures should not be performed in the setting of

acute illness, trauma or surgery or when the patient is on a short

course of blood glucose-raising medication;

Diagnostic tests should be interpreted with caution in patients

taking drugs with hyperglycaemic properties or with treatable

endocrine conditions (Cushing’s syndrome, acromegaly);

If the suspicion of diabetes is high but fasting glucose

concentrations are normal, then an oral glucose tolerance test

(OGTT) should be performed;

If there are normal fasting but raised post-prandial glucose

readings, then diagnosis should be according to 2-hour OGTT

criteria;

Gestational diabetes (diabetes first diagnosed in pregnancy) is an

entity in its own right. Even if the OGTT returns completely to

normal after childbirth, these subjects have an increased risk of

developing type 2 diabetes in later life.