ABSTRACT
Introduction There are no anticoagulants with defined indications for use during percutaneous peripheral intervention (PPI). The endovascular treatment of peripheral arterial disease expands from simple procedures such as renal artery stenting to more complex interventions such as those required to treat acute critical limb ischemia (CLI), deep vein thrombosis (DVT), and acute stroke. The disease states range from focal severe atherosclerotic stenosis to thrombus-laden lesions within diffusely diseased large to small lumen arteries. Depending on the complexity of the PPI, total procedure time also varies from relatively short to very long. All these factors must be considered when deciding the optimal choice of anticoagulant for a peripheral vascular intervention.
