ABSTRACT

Recent advances in prenatal imaging technologies, such as transvaginal ultrasound, threedimensional ultrasound and magnetic resonance imaging (MRI), have been remarkable and have contributed to the prenatal evaluation of fetal abnormalities in utero. Owing to these technologies, fetal malformations have been reliably diagnosed with increasing accuracy and at an earlier gestation. As for the fetal central nervous system (CNS) assessment; a new field of ‘neurosonography’ 1 has been established. Many congenital CNS anomalies, which were disclosed in late pregnancy or after birth, have been demonstrated recently by use of high-frequency transvaginal sonography before viability. More advances in technological development will clarify unknown neuropathological facts during the fetal period.