ABSTRACT
Prostate-specific antigen (PSA) bounce is an extremely interesting and very common phenomenon that has been recognized in men treated for prostate cancer with brachytherapy,1-5 as well as external beam irradiation alone.6,7 PSA bounce is defined by a temporary postirradiation PSA rise of benign etiology.1 PSA bounce causes two major issues: anxiety in men treated with irradiation for prostate cancer and a problem for physicians who must sort PSA bounce from treatment failure. In our experience, anxiety caused by bounce can be minimized by educating men about this issue before and after irradiation for prostate cancer. Consequently, all physicians who have contact with men given irradiation for prostate cancer should be aware of PSA bounce. This report describes PSA bounce after brachytherapy for prostate cancer.
