ABSTRACT

ABP-280 actin-binding protein 280 (thrombin-activated) Ang-1 angiopoietin-1 bFGF basic fibroblast growth factor CAM chick chorioallantoic membrane egr-1 early growth response 1 gene FAK focal adhesion kinase FBG fibrinogen FVa activated factor V FVII factor VII FVIIa activated factor VII FX factor X FXa activated factor X HBD heparin-binding domain HUVEC human umbilical vein endothelial cell MAPK mitogen-activated protein kinase MMP-2 matrix metalloproteinase 2 PAR protease-activated receptor PI3-K phosphatidylinositol 3-kinase PKC protein kinase C SCID severe combined immunodeficient TF tissue factor TFPI tissue factor pathway inhibitor TM thrombomodulin TNF-α tumor necrosis factor-α TSP thrombospondin VE-cadherin vascular endothelial cadherin VEC vascular endothelial cell VEGF/VPF vascular endothelial growth factor/vascular permeability factor VEGFR-2 vascular endothelial growth factor receptor 2 VTE venous thromboembolism XLF cross-linked fibrin (thrombin-activated, factor XIIIa-mediated)