ABSTRACT

Small lymphoid nodules inside the mucosa lining the gastrointestinal tract are normal endoscopic findings among children.1 However, greatly enlarged lymphoid nodules or a mass covering most of the view area and described as lymphoid nodular hyperplasia (LNH) may be considered abnormal. The most typical sites for LNH are the bulb of the duodenum, the colon and the terminal ileum, where small nodules are visible in nearly all subjects.2,3 Assessment by videoendoscope has made LNH now perhaps the most common finding seen in pediatric examinations. During the era of X-ray examinations and fiberoscopes only heavy accumulations of lymphoid tissue were diagnosed, most cases with minor lesions remaining undiagnosed.4 As we may examine only patients with long-term symptoms, for understandable reasons, we will never know the true prevalence of LNH in healthy subjects.