ABSTRACT
The survival rates of patients with chronic intestinal pseudo-obstruction are inferior, being 87 and 70%, respectively. Although long-term PN is associated with complications such as liver impairment, bone disease, vascular thrombosis and sepsis, innovative therapeutic modalities are required. Indeed, some patients develop complications while receiving standard therapy for intestinal failure and are considered for intestinal transplantation. Indications for intestinal transplantation involve mostly pediatric patients and may be divided into three main group: short-bowel syndrome, intestinal motility disorders and congenital diseases of the epithelial mucosa.
