ABSTRACT
Over the years, various histopathological systems combined with descriptive vernacular have been used to describe vascular lesions. Changes in nomenclature and inconsistencies in terminology have led to confusion and misunderstanding among medical specialists, making it difficult to compare published literature describing pathology, treatment and outcomes. A comprehensive biological classification system proposed in 1982 correlated endothelial and mast cell kinetics of vascular lesions with their clinical characteristics and natural history.1 With minor modifications, this classification system is now universally accepted by those at the forefront of this specialized field and is used to classify all vascular lesions in infancy and childhood.
