ABSTRACT
Gamete intrafallopian transfer (GIFT) was one of the first techniques introduced in the late 1970s to assist infertile couples with underlying tubal and unexplained infertility. However, a disadvantage with GIFT was the inability to assess successful fertilization before transfer.1 Zygote intrafallopian transfer (ZIFT), a modification of GIFT, was subsequently developed as an alternative that allows assessment of fertilization. Devroey et al2 reported in 1986 the first pregnancy following ZIFT. Although the ZIFT technique was originally aimed specifically to treat couples with an underlying male factor and who had unsuccessful GIFT procedures, it was quickly expanded to include all infertility etiologies.
