ABSTRACT

The process of implantation is a finely orchestrated series of events involving two major players-the embryo and the maternal endometrium. Embryo maternal dialogue has been the topic for many studies1 as also the fascinating fact that the embryo being a semiallograft is not rejected.2,3,4,5

It was the theory of Medawar in 1950’s that first helped to understand the concept of immune modulation during the process of mammalian implantation. Ever since then there is a constant endeavour to unfold the mystery of this intriguing process.