ABSTRACT
Introduction Recent advances in the understanding of stem cell biology have underscored the great clinical potential of cardiac stem cell therapy. The discovery that human adults retain the capacity for cardiac repair and vasculogenesis has broadened the horizon for the treatment of ischemic heart disease. However, the challenges facing cardiac stem cell therapy are multiple: What is the ideal stem cell? How many cells should be given? And, specific to the present discussion, how should those cells be given?
