ABSTRACT

Patient profile Peter is a 42-year-old man who had had three myocardial infarctions at ages 29, 32, and 33 years. His myocardial function was so compromised after the last episode that he was considered for a heart transplant, which was performed at age 34 years. He had a lipid abnormality for which he had been receiving treatment with a statin. After the transplant, statin therapy was stopped because of a concern that the cyclosporin he was taking to prevent organ rejection may interact adversely with the statin. He was referred to the Lipid Clinic in December 1997, 4 months after the transplant. His plasma lipids at this time were: LDL-cholesterol 9.6 mmol/l, HDL-cholesterol 0.6 mmol/l, and triglyceride 5.7 mmol/l.