ABSTRACT

Case study The patient was an asymptomatic 60-year-old woman who was recently diagnosed as having type 2 diabetes mellitus. She was prompted to have a health check because her elder brother who was also a diabetic had just had a myocardial infarction at the age of 63. She was a nonsmoker and had a history of hypertension for 7 years and had been treated with a calcium channel blocker.There was a strong family history of type 2 diabetes. Her mother, elder brother, and a younger sister were diabetic. Physical examination showed that her weight and height were 69 kg and 157 cm, respectively. Blood pressure was 155/90 mm Hg. She had mild background retinopathy and the rest of the examination was unremarkable. Urinalysis showed 1 + glucose and 1 + proteinuria. Investigations showed a fasting glucose 10.5 mmol/l, HbA1c 9.2%, normal renal function, total cholesterol 6.0 mmol/l, fasting triglyceride 3.0 mmol/l, LDL-cholesterol 3.5 mmol/l, HDL-cholesterol 1.1 mmol/l, apolipoprotein (apo) AI 1.24 g/l, apoB 1.30 g/l, and proteinuria 0.5 g/day. ECG and exercise test were negative.