ABSTRACT
Atopic dermatitis (AD) belongs to a family of chronic inflammatory skin diseases that have been known for more than 2000 years but recognized as an individual entity at the end of the nineteenth century. Despite the tremendous progress made in the field of immunology and allergology during the last 30 years, we still face a complex and fascinating disease which consistently offers new challenges for physicians and researchers. In this concluding chapter, we felt it was necessary to state some of the most important and remaining open questions that must be addressed since they will have a major impact on how research in the field of AD will progress in the future.
