ABSTRACT

Mohs micrographic surgery, which was first described by Mohs in 1941 (1), is a highly effective therapeutic modality for the surgical extirpation of certain cutaneous malignancies. The ‘‘fresh tissue technique’’ (2), which is currently utilized by most Mohs surgeons, involves the saucerization excision of a neoplasm followed by the preparation of horizontal frozen sections, sequential microscopic examination of all frozen section tissue specimens, meticulous mapping of the excised tissue, and reexcision of persistent tumor until all margins are clear. Implicit in the Mohs technique is the examination of the entire peripheral and deep margin of the excisional specimen, thus ensuring maximal cure rates and the conservation of normal tissue.