Electrophysiological Mechanisms Relating to Pharmacological Therapy of Atrial Fibrillation

As a cardiac arrhythmia, atrial fibrillation (AF) is undoubtedly at the crossroads (1,2). For many decades, it commanded relatively little attention. AF is the most common arrhythmia requiring hospitalization, and its association with significant mortality and morbidity has led to heightened clinician awareness of this important arrhythmia (3-6).