ABSTRACT
INTRODUCTION Allergic bronchopulmonary aspergillosis (ABPA) is a lung disease caused by an immunologic response to the mold Aspergillus fumigatus, and rarely other Aspergillus species. The disease is mostly described in genetically susceptible asthmatics and cystic fibrosis (CF) patients. An exaggerated host immune response involving Th2 CD4+T-cells, IgE and IgG antibodies is central to the pathogenesis of ABPA. The diagnosis of ABPA is often difficult and requires the combination of clinical, radiographic, and laboratory criteria.
