ABSTRACT
This chapter discusses the consequences of high-dose radiation to these structures. Though most published data refer to the “classic” implantation of the prostate with permanent sources such as iodine and palladium, the same patterns are also likely to be seen with the newer forms of temporary high dose-rate brachytherapy using iridium. Two broad approaches can be taken to the implantation of sources within the prostate. The first, or preplanned technique, begins with a “volume study” prior to the day of the implant. Urinary symptoms are among the most commonly reported side effects following brachytherapy. Most patients develop some degree of urinary irritative or obstructive symptoms, including urinary frequency, urgency, dysuria, incomplete voiding, weak stream, or less commonly, acute urinary retention. Gross hematuria is common in patients immediately following seed implantation and is generally of little clinical significance. Occasionally, patients will develop urinary retention, requiring catheter placement and bladder irrigation.
