ABSTRACT

Jean Martin Charcot, in 1883, first described Charcot neuroarthropathy as occurring in patients with tabes dorsalis. Charcot neuroarthropathy was not known to be associated with diabetes until William Reily Jordan noted the connection in 1936 (1). Although two-thirds of patients with Charcot neuroarthropathy have type 2 diabetes, many other causes have been reported [e.g., syphilis (i.e., tabes dorsalis), leprosy, alcoholism, peripheral nerve injuries, spina bifida, folate deficiency (e.g., pernicious anemia), and spinal cord lesions (e.g., syringomyelia, posttraumatic cord injury, meningomyelocele, and disk herniation)] (2).