ABSTRACT
This monograph is largely concerned with patterns of illness, pathophysiology, and management of chronic rhinosinusitis (CRS). It is important to realize that CRS does not occur alone but may, in many instances, exist in association with other medical conditions or comorbidities. Some of these associated conditions may predispose to the development of CRS. Some may be worsened by the presence of CRS. Finally, some may simply be seen as co-existent. It is the intent of this chapter to discuss four co-morbid conditions commonly seen in CRS, to delve into the pathophysiologic mechanisms, and finally deal with their management.
