ABSTRACT
Topical retinoids are singularly important agents in the treatment of acne vulgaris. Any molecule having a biological effect through the binding and activation of retinoid receptors is considered a retinoid (1). This class of medications includes vitamin A and all synthesized molecules that are derived from it (1). By influencing DNA transcription, retinoids can modify cellular growth and differentiation, immunomodulation, and tumor promotion. In turn, they improve acne vulgaris by inhibiting microcomedone formation, diminishing the number of mature comedones as well as inflammatory lesions, and normalizing follicular epithelium maturation and desquamation (2).
