ABSTRACT

The potential hazard of toxicants to the male reproductive system is well established (Table 1) (1-3). A toxicant, whether a chemical, physical, or biological agent, acts by interrupting biological processes either by a direct chemical action or indirectly via metabolic products by altering physiological control systems (4). In the male reproductive system, such an interruption can occur at any level of the hypothalamic-pituitarytesticular axis, or alternatively, by altering posttesticular events such as sperm motility and/or function. Any disruption of these events by toxicants may lead to hypogonadism and/or infertility (3).