ABSTRACT

This is a period of tremendous excitement in the schizophrenia genetics field and the next few years may enable discoveries that impact directly on the clinician’s work. In this chapter, we have first provided the background for such research that should usefully complement the concepts provided in other chapters. An update on current gene-mapping efforts for schizophrenia follows. We have highlighted recent successes with selected “candidate genes.” We have also summarized efforts to map genes for traits that usefully complement the conventional diagnostic phenotype. We conclude by summarizing the implications of this work for the practicing clinician.